发明名称 Ketamine analogues for the treatment of thrombocytopenia.
摘要 <p>5,6-Dehydronorketamine and derivatives retaining the alpha , beta -unsaturated carbonyl are disclosed. These and other Michael or Michael-type acceptors and adducts are shown to influence the replication, differentiation or maturation of blood cells, especially platelet progenitor cells. Accordingly, these compounds are used for treatment of thrombocytopenia.</p>
申请公布号 EP0623343(A1) 申请公布日期 1994.11.09
申请号 EP19930303557 申请日期 1993.05.07
申请人 GENENTECH, INC. 发明人 KOGAN, TIMOTHY P.;SOMERS, TODD C.
分类号 A61K31/00;A61K31/12;A61K31/135;C07C225/20;C07C323/60;C07D495/04;(IPC1-7):A61K31/00 主分类号 A61K31/00
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