发明名称 |
Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression |
摘要 |
This invention is a method for encapsulating nucleic acids linked to or co-existing with other molecules that facilitate the uptake and integration of genetic material into living cells by means of slow-release of DNA/RNA or oligonucleotides combined with cell surface ligands/proteins/transcription factors and antibodies. Compositions for use with this method are disclosed. |
申请公布号 |
AU6707194(A) |
申请公布日期 |
1994.11.08 |
申请号 |
AU19940067071 |
申请日期 |
1994.04.19 |
申请人 |
MEDISORB TECHNOLOGIES INTERNATIONAL L.P. |
发明人 |
SANDRA GERTRUDE MCELLIGOTT;MICHAEL DAVID AMOS |
分类号 |
C12N15/09;A61K9/16;A61K9/52;A61K31/70;A61K38/00;A61K47/48;A61K48/00;C07H21/04;C07K14/61;C12N15/82;C12N15/87 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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