Hepatitis c virus immunodiagnostic antigens and antibodies

摘要

Antigen and antibody compositions immunoreactive with hepatitis C virus infected sera are disclosed. The antigen composition include a peptide corresponding to the predicted NS5 protein of HCV. The antibody composition contains monoclonal antibodies immunoreactive with several epitopes of this antigen. The antigens are useful in generating antibodies for use in antigen-inhibition immunodiagnostic methods for detecting the presence of HCV antigens in test samples.