发明名称 N-ALKYLATED QUATERNARY NITROGEN-CONTAINING HETEROCYCLES
摘要 The synthesis of 4-, 4-(1,1)- and 3,5- substituted N-alkyl-pyri-dinium salts as well as of 2-carboxamide substituted N(1,4)diazinium componunds are described. The N-surfactants obtained have a small critical micelle concentration (CMC) of 10-5 - 10-7 Mol/ Liter. These surfactants produce micells of different size and form depending on the nature of the anions. 4-(1,1)-substituted and 3,5-substituted N-alkyl-pyridinium components are capable of forming vesicles in equeous solutions of different forms and sizes. The N-surfactants synthesized can be used as pharmaceuticals.
申请公布号 CA1332940(C) 申请公布日期 1994.11.08
申请号 CA19870543936 申请日期 1987.08.06
申请人 MEDICE CHEM.-PHARM. FABRIK PUETTER GMBH & CO. KG 发明人 PARADIES, HENRICH H.
分类号 A61K31/70;A61K9/10;A61K9/107;A61K9/127;A61K31/375;A61K31/395;A61K31/41;A61K31/415;A61K31/4184;A61K31/425;A61K31/426;A61K31/428;A61K31/44;A61K31/4418;A61K31/4425;A61K31/46;A61K31/47;A61K31/49;A61K31/496;A61K31/505;A61K31/52;A61K31/522;A61K31/53;A61K31/65;A61K31/66;A61K33/24;A61K33/28;A61K33/30;A61K33/42;A61K45/08;A61K47/00;A61K47/18;A61K47/22;A61P17/00;A61P17/16;A61P31/04;A61P31/12;A61P35/00;A61P43/00;B01F17/18;B01F17/32;C07C67/00;C07C213/00;C07C217/08;C07D213/20;C07D213/30;C07D213/63;C07D213/65;C07D213/68;C07D213/69;C07D213/73;C07D213/79;C07D213/80;C07D213/81;C07D213/82;C07D215/10;C07D215/18;C07D231/12;C07D231/18;C07D231/20;C07D231/28;C07D233/54;C07D233/58;C07D235/06;C07D239/26;C07D239/30;C07D239/36;C07D239/46;C07D239/47;C07D239/54;C07D239/553;C07D241/12;C07D241/18;C07D241/24;C07D249/08;C07D251/18;C07D251/70;C07D277/22;C07D277/62;C07D307/62;C07D471/04;C07D473/00;C07D473/04;C07D473/06;C07D473/16;C07D473/18;C07D473/28;C07D473/30;C07D473/32;C07D473/34;C07D473/38;C07D473/40;C07D487/04;C07D521/00;C12N9/99;G01N33/52;G01N33/532;G01N33/543;G01N33/544;G01N33/58;(IPC1-7):C07D213/68 主分类号 A61K31/70
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