| 发明名称 |
Process for 4''-EPI-acetylamino-4''-deoxy-5-oximinoavermectin-B1 |
| 摘要 |
An improved process for formation of a 5-oxime on avermectin derivatives comprises the treatment of the oxo compound with O-(trimethylsilyl)hydroxylamine in the presence of a Lewis acid.
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| 申请公布号 |
US5362862(A) |
申请公布日期 |
1994.11.08 |
| 申请号 |
US19930128935 |
申请日期 |
1993.09.29 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
AMATO, JOSEPH S.;CVETOVICH, RAYMOND |
| 分类号 |
C07H19/01;(IPC1-7):C07H17/04;A61K31/70 |
主分类号 |
C07H19/01 |
| 代理机构 |
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