A syringe holder for a conventional disposable syringe. The holder includes a needle assembly having a retractable needle for preventing accidental needle pricks. The needle assembly mounts to the forward end of a carrier having a chamber for receiving a hypodermic syringe. A plunger is slidably mounted in the carrier for moving the syringe between a loading/unloading position and a "use" position. As the hypodermic syringe is moved from its loading/unloading position to its "use" position, the hypodermic needle is extended through an aperture in the needle cap to expose the hypodermic needle. A locking means locks the hypodermic syringe in the "use" position during administration of medication to or drawing fluid from a patient. After use, the locking means is released and the needle is urged to a retracted position by a biasing means. The needle assembly and hypodermic syringe then are discarded.