发明名称 DNA sequencing
摘要 To sequence DNA, DNA samples marked with fluorescent infrared dye are applied at a plurality of locations for electrophoresing in a plurality of channels through a gel electrophoresis slab. The channels are scanned with a laser and a sensor, that include a microscope focused on the gel slab. The focal point and slab are adjusted with respect to each other so that the focal point of the microscope remains on the gel slab during a scan. The data from the scan is directly used to amplitude modulate density readings on a display, and the scan is displayed in a horizontal sweep of a cathode ray tube, whereby said cathode ray tube provides intensity displays of bands representing DNA. Different sizes of glass gel sandwiches may be mounted to the same console for different sequencing tasks.
申请公布号 US5360523(A) 申请公布日期 1994.11.01
申请号 US19930018806 申请日期 1993.02.17
申请人 LI-COR, INC. 发明人 MIDDENDORF, LYLE R.;BRUCE, ROBERT C.;ECKLES, ROBERT D.
分类号 C07D209/60;C09B23/01;C12Q1/68;G01N21/64;G01N27/447;(IPC1-7):G01N27/26 主分类号 C07D209/60
代理机构 代理人
主权项
地址