NOVEL BIOACTIVE SUBSTANCE MK7607 AND ITS PRODUCTION

摘要

PURPOSE:To provide the novel bioactive substance produced by culturing an MK7607-producing fungus belonging to Curvularia and collecting the product from the cultured material, having an effective herbicidal activity on various kinds of weeds and free from a fear of residue on a crop or environmental pollution. CONSTITUTION:An MK7607-producing fungus [e.g. Curvularia eragrostidis D2452 (FERM-P-13557)] belonging to Curvularia is inoculated in a culture medium and subjected to stationary culture at 26 deg.C for 2day. The resultant cell body is added to 50% acetone water, stirred for an hour and subsequently filtered to obtain an extract of the fungus. The acetone is then distilled off under vacuum from the obtained fungus extract and the resultant concentrated solution is subsequently treated with butanol to remove liposoluble components. The aqueous layer is treated with active carbon and subsequently concentrated and the resultant residue is purified according to the chromatography method, thus producing a new bioactive substance MK7607 represented by the formula and having an effective herbicidal activity on various kinds of weeds.