| 摘要 |
<p>A transgenic animal, whose germ cells and stomatic cells contain a transgene including a DNA sequence encoding a CD28 ligand and a tissue-specific promoter operably linked to the DNA sequence, wherein the tissue-specific promoter effects expression of the CD28 ligand in cells of a specific tissue of the animal is disclosed. This animal serves as a transgenic model for specific autoimmune diseases.</p> |
