摘要 |
<p>A process for regioselectively producing a lignan compound of general formula (I) by reacting a lactone compound of general formula (II) with a compound of the formula: R7Cl (R7 being a tri(lower alkyl)silyl group) in the presence of a base, effecting the addition reaction of an acetylene compound of general formula (III) with the resultant compound, and reducing the product. In said formulas R1 represents alkyl, cycloalkyl, cycloalkyl-lower alkyl, aralkyl, etc.; R?2 and R3¿ each represent lower alkoxy, etc.; R4 represents lower alkoxy or hydrogen; and R?5 and R6¿ each represent lower alkyl.</p> |