METHOD FOR MAKING A BIOERODIBLE MATERIAL FOR THE SUSTAINED RELEASE OF A MEDICAMENT AND THE MATERIAL MADE FROM THE METHOD

摘要

A method for making an implantable bioerodible material for the sustained release of a medicament and the material made from the method. The method comprises the formulation of a biomaterial polymeric carrier into particles of predetermined density and size. The particles are then mixed with the desired medicament and extruded into the desired shape for implantation or reground to a predetermined size distribution for injection as a suspension. In an alternative embodiment, the particles of polymeric carrier are immersed in a solvent containing a medicament, and the pores of the particles are filled with medicament through alternate application and release of vacuum. The invention is disclosed in a flowchart which outlines the steps of formulating the bioerodible material.