CANCER THERAPY, USING ANTIBODY CONJUGATES, IN COMBINATION WITH A VASOACTIVE AGENT

摘要

The invention provides a two component system for the treatment of cancer comprising: (i) a tumour-directed antibody linked to a toxic agent or linked to an enzyme capable of converting a prodrug to a toxic agent; and (ii) an agent having the ability to restrict blood flow at the site of a tumour. Preferably the agent is a flavonoid derivative such as 5,6 dimethylxanthenone acetic acid or flavone acetic acid.