Compounds of general formula (I) wherein X is -CONHOH or -CO2H, principally characterised by the presence in substituent R3 and/or R4 of a group of formula (II) are inhibitors of matrix metalloproteinases and inhibitors of the production of tumour necrosis factor.
申请公布号
WO9424140(A1)
申请公布日期
1994.10.27
申请号
WO1994GB00808
申请日期
1994.04.18
申请人
BRITISH BIO-TECHNOLOGY LIMITED;CRIMMIN, MICHAEL, JOHN;AYSCOUGH, ANDREW, PAUL;BECKETT, RAYMOND, PAUL
发明人
CRIMMIN, MICHAEL, JOHN;AYSCOUGH, ANDREW, PAUL;BECKETT, RAYMOND, PAUL