| 发明名称 |
NEURAL THREAD PROTEIN GENE EXPRESSION AND DETECTION OF ALZHEIMER'S DISEASE |
| 摘要 |
The present invention is directed to recombinant hosts expressing novel proteins associated with Alzheimer's Disease, neuroectodermal tumors, malignant astrocytomas, and glioblastomas. This invention is specifically directed to the recombinant hosts and vectors which contain the genes coding for the neuronal thread proteins. This invention is also directed to substantially pure neural thread protein, immunodiagnostic and molecular diagnostic methods to detect the presence of neural thread proteins, and the use of nucleic acid sequences which code for neural thread proteins in gene therapy. |
| 申请公布号 |
CA2161097(A1) |
申请公布日期 |
1994.10.27 |
| 申请号 |
CA19942161097 |
申请日期 |
1994.04.20 |
| 申请人 |
GENERAL HOSPITAL CORPORATION (THE) |
发明人 |
DE LA MONTE, SUZANNE M.;WANDS, JACK R. |
| 分类号 |
C12N15/09;A61K31/70;A61K35/74;A61K48/00;A61K49/00;A61K51/00;A61P25/28;C07H21/04;C07K14/435;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12P21/02;C12Q1/68;G01N33/53;G01N33/577;G01N33/68;(IPC1-7):C12N15/12;C12N15/70;C07H21/00;G01N33/574;G01N33/566 |
主分类号 |
C12N15/09 |
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