| 发明名称 |
HETEROCYCLIC DERIVATIVES IN THE TREATMENT OF ISCHAEMIA AND RELATED DISEASES |
| 摘要 |
Novel substituted piperidines and piperazines or the pharmaceutically acceptable acid addition salts thereof, are calcium and/or sodium channel antagonists useful for treating mammals having a variety of disease states, such as stroke, epilepsy, hypertension, angina, migraine, arrhythmia, thrombosis, embolism, and also for treatment of spinal injuries. |
| 申请公布号 |
WO9424116(A1) |
申请公布日期 |
1994.10.27 |
| 申请号 |
WO1994EP01085 |
申请日期 |
1994.04.06 |
| 申请人 |
SYNTEX PHARMACEUTICALS LIMITED |
发明人 |
MCCORT, GARY;PASCAL, JEAN-CLAUDE;BLONDET, DOMINIQUE;GELLIBERT, FRANCOISE |
| 分类号 |
C07D295/02;A61K31/135;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/435;A61K31/443;A61K31/445;A61K31/451;A61P9/00;A61P9/10;A61P9/12;A61P13/02;A61P15/00;A61P25/02;A61P25/28;C07C209/04;C07C209/50;C07C211/27;C07C211/29;C07C217/62;C07D207/32;C07D207/333;C07D207/335;C07D211/10;C07D211/46;C07D211/54;C07D211/58;C07D277/22;C07D295/03;C07D295/06;C07D295/073;C07D295/08;C07D295/096;C07D295/135;C07D307/46;C07D307/52;C07D333/20;C07D333/22;C07D405/06;(IPC1-7):C07D295/073;A61K31/535;A61K31/495 |
主分类号 |
C07D295/02 |
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