发明名称 Method of preparing fusion proteins
摘要 Fusion proteins are obtained in high yields if a mixed oligonucleotide is constructed which codes for the ballast constituent of the fusion protein. The oligonucleotide mixture is introduced in a vector in such a manner that it is functionally linked to a regulatory region and to the structural gene for the desired protein. Appropriate host cells are transformed with the plasmid population obtained in this manner and the clones producing a high yield of coded fusion protein are selected.
申请公布号 US5358857(A) 申请公布日期 1994.10.25
申请号 US19930073508 申请日期 1993.06.09
申请人 THE GENERAL HOSPITAL CORP.;HOECHST AKTIENGESELLSCHAFT 发明人 STENGELIN, SIEGFRIED;HABERMANN, PAUL;UHLMANN, EUGEN;SEED, BRIAN
分类号 C07K14/62;C12N15/12;C12N15/62;(IPC1-7):C12N15/12 主分类号 C07K14/62
代理机构 代理人
主权项
地址