| 摘要 |
Compounds of the formula <IMAGE> or a pharmaceutically acceptable salt or ester thereof, wherein R1 is selected from the group consisting of hydrogen and C1-10 alkyl; R2 is selected from the group consisting of hydrogen and C1-10 alkyl; R3 is selected from the group consisting of C1-10 alkoxyl, C1-10 alkyl and cyano; R4 is selected from the group consisting of C1-10 alkenyloxyl, C1-10 alkoxyl, C1-10 alkyl, C1-10 alkylcarbamic, C1-10 alkylcarbonyloxyl, carbonyl, hydroxyl, and -NHR5, and R5 is selected from the group consisting of hydrogen and C1-10 alkylcarbonyl. Such compounds are useful as selective antagonists of testosterone 5 alpha -reductase 1.
|
