发明名称 |
Process for preparing alkyl-L-alanyl-L-proline derivatives |
摘要 |
A process for preparing N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxy anhydride from N-[1(S)-ethoxycarbonyl-3 -phenylpropyl]-L-alanine and N,N'-carbonyldiimidazole and the condensation thereof with L-proline silyl ester hydrochloride. The condensation product is used as an angiotensin converting enzyme (ACE) inhibitor.
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申请公布号 |
US5359086(A) |
申请公布日期 |
1994.10.25 |
申请号 |
US19930122709 |
申请日期 |
1993.09.16 |
申请人 |
KRKA, PHARMACEUTICAL & CHEMICAL WORKS |
发明人 |
MERSLAVIC, MARJO;CRINSKI, JANJA |
分类号 |
C07D207/16;(IPC1-7):C07D207/12 |
主分类号 |
C07D207/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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