发明名称 |
Modified oligonucleotides having improved anti-influenza activity |
摘要 |
The invention provides anti-influenza modified oligonucleotides that have greater efficacy in inhibiting influenza replication or propagation than previously described oligonucleotides. The greater efficacy arises from structural features such as chimeric or hybrid backbones, nuclease resistance-conferring terminal capping structures and/or self-complementary regions. |
申请公布号 |
AU6527094(A) |
申请公布日期 |
1994.10.24 |
申请号 |
AU19940065270 |
申请日期 |
1994.03.30 |
申请人 |
HYBRIDON, INC. |
发明人 |
SUDHIR AGRAWAL;JIN-YAN TANG;ABEYSINGHE PADMAPRIYA |
分类号 |
C12N15/09;A61K31/70;A61K48/00;A61P31/12;A61P31/16;C07H21/00;C07H21/04;C12N15/113 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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