Water-insoluble cyclodextrin polymers and processes for their preparation

摘要

PCT No. PCT/EP91/00562 Sec. 371 Date Sep. 25, 1992 Sec. 102(e) Date Sep. 25, 1992 PCT Filed Mar. 22, 1991 PCT Pub. No. WO91/14710 PCT Pub. Date Oct. 3, 1991.A hydrophilic, water-dilatable cyclodextrin polymerizate has a high cyclodextrin content which possesses good mechanical properties. The cyclodextrin pearl polymerizates are produced by radical, inversion suspension polymerization of cyclodextrin derivatives carrying methacrylate groups or their copolymerization with suitable comonomers such as hydroxyethylacrylate or hydroxymethylacrylate. Suitable cyclodextrin derivatives can be produced by reacting cyclodextrins or hydroxyalkyl cyclodextrins with methacrylic anhydride or with glycidyl methacrylate. The cyclodextrin polymerizates produced in this manner have mechanical properties appreciably superior to those of known, comparable cyclodextrin polymers.