SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION

摘要

SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION A sustained-release pharmaceutical composition which comprises microparticles comprising an active principle, said microparticles being coated with a coating mixture comprising ethyl cellulose and an acrylic resin which is a polymerisate of acrylic and methacrylic ester, having a molecular weight of at least 100,000 and comprising units of formula: <IMG> wherein: R1 is hydrogen or methyl, R2 is methyl or ethyl, R3 is methyl; and R4 is -CH2-CH2N(CH3)3Cl the resin containing 5% of trimethylammonium methacrylate chloride units by weight.