| 发明名称 |
GIBBON APE LEUKEMIA VIRUS-BASED RETROVIRAL VECTORS |
| 摘要 |
The present invention provides replication-defective hybrid retroviral vectors comprising GaLV components and methods for preparing and using such vectors. The vectors comprise an envelope component, a core component and a defective genome, at least one of which is derived from GaLV. The vectors can comprise the minimal cis acting sequences from GaLV that allow packaging of the defective genome in a hybrid virion.
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| 申请公布号 |
CA2160034(A1) |
申请公布日期 |
1994.10.13 |
| 申请号 |
CA19942160034 |
申请日期 |
1994.04.06 |
| 申请人 |
GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (THE) |
发明人 |
EIDEN, MARYBETH V.;WILSON, CAROLYN A.;DEACON, NICHOLAS J.;HOOKER, DAVID J. |
| 分类号 |
C12N15/09;A61K31/70;A61K35/76;A61K48/00;C07H21/04;C07K14/15;C12N5/10;C12N7/00;C12N7/01;C12N15/48;C12N15/867;(IPC1-7):C12N15/86;C12N7/04 |
主分类号 |
C12N15/09 |
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