RECOMBINANT .ALPHA.-N-ACETYLGALACTOSAMINIDASE ENZYME AND CDNA ENCODING SAID ENZYME

摘要

This invention relates to a recombinant enzyme for use in the removal of A antigens from the surface of cells in blood products. Specifically, this invention is directed to a recombinant .alpha.-N-acetylgalactosaminidase enzyme from chicken liver, methods of cloning and expressing said recombinant .alpha.-N-acetylgalactosaminidase enzyme and a method of removing A antigens from the surface of cells in blood products using said recombinant .alpha.-N-acetylgalactosaminidase enzyme.