发明名称 |
DNA encoding a human thrombomodulin having a modified glycosaminoglycan (GAG) binding site |
摘要 |
Thrombin-binding substances capable of promoting anti-thrombin III activity and inhibiting platelet aggregation, and by themselves possessing anti-thrombin activity are disclosed. The thrombin-binding substances are useful as an effective component of anticoagulant agents, and can be produced inexpensively on a large scale.
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申请公布号 |
US5354664(A) |
申请公布日期 |
1994.10.11 |
申请号 |
US19930110011 |
申请日期 |
1993.08.23 |
申请人 |
KOWA CO., LTD. |
发明人 |
DOI, TAKESHI;IWASAKI, AKIO;SAINO, YUSHI;KIMURA, SHIGERU;OHKUCHI, MASAO |
分类号 |
A61K38/00;C07K14/745;C12N15/12;C12N15/15;(IPC1-7):C12N15/15;C12N5/10 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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