发明名称 |
Antisense molecules directed against a tenascin gene |
摘要 |
The present invention is directed to a polynucleotide of less than about 50 nucleic acid bases in length, which polynucleotide hybridizes to the tenascin gene. The present invention is also directed to a pharmaceutical composition comprising the above polynucleotide dissolved or dispersed in a physiologically tolerable diluent. The present invention is further directed to a process for inhibiting vascular smooth muscle cell proliferation which process comprises inhibiting the expression of tenascin in vascular smooth muscle cells. |
申请公布号 |
AU6524294(A) |
申请公布日期 |
1994.10.11 |
申请号 |
AU19940065242 |
申请日期 |
1994.03.24 |
申请人 |
TEXAS BIOTECHNOLOGY CORP. |
发明人 |
LARRY A DENNER;AJAY A REGE;RICHARD A.F. DIXON;DAVID L STACY |
分类号 |
C07H21/00;C12N15/113 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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