发明名称 |
2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
摘要 |
The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: <IMAGE> Formula I which are useful as analgesic agents for the treatment of pain, and for prostaglandin-E2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal, and a method for treating prostaglandin-E2 mediated diseases in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
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申请公布号 |
US5354747(A) |
申请公布日期 |
1994.10.11 |
申请号 |
US19930079021 |
申请日期 |
1993.06.16 |
申请人 |
G. D. SEARLE & CO. |
发明人 |
HANSEN, JR., DONALD W.;PETERSON, KAREN B. |
分类号 |
C07D267/20;C07D281/16;C07D413/06;C07D413/12;C07D413/14;C07D417/06;C07D417/12;C07D471/04;(IPC1-7):C07D413/06;A61K31/55 |
主分类号 |
C07D267/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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