摘要 |
Compounds of general formula (II) wherein R<3> is C1-35 hydrocarbyl group optionally substituted by one to five substituents, selected from halo, C1-6alkoxy, hydroxy, amino, and mono- or di-C1-4alkyl-amino; and either the dotted line represents a double bond between the 2 and 3 positions of the naphthyl ring; R<1> and R<4> each represent = O; and R<2> represents a group (a) wherein n is 2 or 3, R<6> and R<7> which may be the same or different, each represent a hydrogen atom, a C1-6alkyl group, optionally substituted by hydroxy, C1-6alkoxy or a group (b) wherein R<9> is a C1-6alkyl group optionally substituted by an amino group optionally substituted by one or two alkyl groups, or R<6> and R<7> may each be a group (c) wherein R<8> is a C1-6alkyl group, A is an oxygen atom or a group (d) wherein R<5> represents a hydrogen atom, a C1-6alkyl group optionally substituted by hydroxy, C1-6 alkoxy or an amino group optionally substituted by one or two C1-6alkyl groups or R<5> is a group (e) wherein R<10> is a C1-6alkyl group or R<5> is a group (f) wherein p is 2 or 3 and R<11> and R<12> are as hereinbefore defined for R<6> and R<7> or, when m is 1 and n is 2 R<5> may be linked to R<6> so that (g) forms a piperazine ring; or the dotted line represents double bonds between the 1, 2 and 3, 4 positions of the naphthyl ring, and R<1>, R<2> and R<4> each represent a group (h) (wherein n, A, R<6> and R<7> are as hereinbefore defined); and physiologically acceptable salts thereof. |