发明名称 |
Sensitive yeast genetic system for identifying agents causing double-stranded DNA damage |
摘要 |
A sensitive, yeast-based genetic system for identifying agents causing double-strand DNA damage is described. The system comprises a yeast strain containing either chromosomes having divergent (homeologous) DNA sequences, a single nonhomologous chromosome or a single artificial chromosome with suitable genetic markers so that double-strand damage leading to the loss of such chromosome due to the inability to undergo recombinational repair with a homolog is detected.
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申请公布号 |
US5352581(A) |
申请公布日期 |
1994.10.04 |
申请号 |
US19920897577 |
申请日期 |
1992.06.11 |
申请人 |
UNITED STATES/NATIONAL INSTITUTES OF HEALTH |
发明人 |
RESNICK, MICHAEL A.;NILSSON-TILLGREN, TORSTON |
分类号 |
C12Q1/18;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12Q1/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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