发明名称 COMPOSITIONS OF IODOPHENYL ESTERS AND IODOPHENYL SULFONATES FOR VISUALIZATION OF THE GASTROINTESTINAL TRACT
摘要 Disclosed are novel iodophenyl carboxylic or sulfonic acid esters of the formula: <IMG> wherein X is -CO- or -SO2-; Z is H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy or cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R is C1-C25 alkyl, cycloalkyl, aryl, or halo-lower-alkyl, each optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy or lower-alkoxy carbonyl, lower-alkenyl, lower-alkynyl, lower-alkylene, lower-alkoxy-carbonyloxy; n is 1-5; y is 0-4; and w is 1-4! useful as x-ray contrast agents in diagnostic radiology of the gastrointestinal tract.
申请公布号 CA2115910(A1) 申请公布日期 1994.10.01
申请号 CA19942115910 申请日期 1994.02.17
申请人 STERLING WINTHROP INC. 发明人 BACON, EDWARD R.;DAUM, SOL J.;ESTEP, KIMBERLY G.;JOSEF, KURT A.;DOUTY, BRENT D.;ILLIG, CARL R.
分类号 A61K49/04;C07C69/017;C07C69/63;C07C69/675;C07C69/708;C07C69/74;C07C69/773;C07C255/55;C07C309/65;C07C309/67;C07C309/68;C07C309/71;C07C309/72;(IPC1-7):C07C69/63;C07C69/96 主分类号 A61K49/04
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