| 摘要 |
<p>NEW MATERIAL:An optically active compound of formula I [A is H, OH-protecting group; B is H, OH-protecting group; X is O, S; R1 is H, alkyl, aryl; the dotted line represents alpha-configuration; the thick solid line represents beta-configuration; the wavy line represents alpha-configuration, beta-configuration or their mixture]. EXAMPLE:(3aR, 5S, 6R, 6aR)-5-Benzoyloxy-1-ethylthio-6-(2-hydroxyethyl)-hexahydro-1H-cyclopen ta(c)furan. USE:Intermediate for the production of a bioactive substance such as prostaglandin or a prostaglandin-family compound. PROCESS:The compound I is prepared by reacting a compound II (A' is H, OH- protecting group) with a compound III in the presence of an acid, and if necessary after protecting the OH group, hydrolyzing the resulting acetal.</p> |
