发明名称 |
Bærer for oligonukleotidsyntese |
摘要 |
<p>A support carrying a homocyclic or heterocyclic ring containing a first and second carbon atom wherein: (i) the first carbon atom is substituted by a nucleophilic group or a group convertible to a nucleophilic group on treatment with base; (ii) the second carbon atom is substituted by a hydroxy group, a hydroxy group protected by an acid labile protecting group, or a phosphate group substituted by an oligonucleotide; and (iii) the first and second carbon atoms are directly connected by a covalent bond; which is suitable for use in oligonucleotide synthesis. Methods for its preparation and use, and novel compounds for attachment to the support are described.</p> |
申请公布号 |
NO943667(D0) |
申请公布日期 |
1994.09.30 |
申请号 |
NO19940003667 |
申请日期 |
1994.09.30 |
申请人 |
ZENECA LTD |
发明人 |
MCLEAN, MICHAEL JOSEPH;GARMAN, ANDREW JOHN |
分类号 |
C07H21/04;C07C59/11;C07D307/20;C07F9/6558;C07F9/6561;C07H21/00;(IPC1-7):C07D307/20;C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|