RIP, process for its preparation and pharmaceutical composition containing the RIP
摘要
The invention relates to a ribosome-inactivating protein (P 1 or peponin) which can be isolated from the seeds of species of gourds. This protein has an action inhibiting HIV reverse transcriptase besides the known ribosome-inactivating activity. The molecular weight of the protein is about 31 kDa, and the protein has an IEP of 8 to 9.
申请公布号
DE4309796(A1)
申请公布日期
1994.09.29
申请号
DE19934309796
申请日期
1993.03.25
申请人
LOMAPHARM RUDOLF LOHMANN GMBH KG, 31860 EMMERTHAL, DE
发明人
WAGNER, HILDEBERT, PROF. DR., 83254 BREITBRUNN, DE;ERFLE, VOLKER, PROF. DR., 81679 MUENCHEN, DE;GERHAEUSER, CLARISSA, DR., 80469 MUENCHEN, DE;OTT, HOLGER, 61479 SCHLOSBORN, DE