| 摘要 |
<p>The present invention relates to the diagnosis of the human inflammatory bowel diseases, Crohn's disease and ulcerative colitis, and to nucleic acid and peptide reagents, detection methods, and pre-packaged kits useful for such diagnosis. Specifically, nucleic acids are presented which may be used to detect the presence of small RNA molecules which are found in ulcerative colitis- and/or Crohn's-diseased tissue, but are absent from, or are present in greatly reduced levels in, the corresponding tissue exhibiting manifestations of these diseases. Further, antibody reagents are presented which may be used to detect the presence of peptides which are found in ulcerative colitis- and/or Crohn's-diseased tissue, but are absent from, or are present in greatly reduced levels in, the corresponding tissue exhibiting manifestations of these diseases.</p> |
