摘要 |
A class of chemical compounds comprising a 1H-indazole moiety and a substituted heterocyclic moiety, linked via the 3-position of the indazole moiety by a methylene group, are ligands for dopamine receptor subtypes within the body and are therefore useful in the treatment and/or prevention of disorders of the dopamine system, in particular schizophrenia. In said formula (I) R represents hydrogen or C1-6 alkyl, Q represents a moiety of formula Qa, Qb or Qc. |
申请人 |
MERCK SHARP & DOHME LIMITED;BAKER, RAYMOND;KULAGOWSKI, JANUSZ, JOZEF;LEESON, PAUL, DAVID;SMITH, ADRIAN, LEONARD |
发明人 |
BAKER, RAYMOND;KULAGOWSKI, JANUSZ, JOZEF;LEESON, PAUL, DAVID;SMITH, ADRIAN, LEONARD |