发明名称 |
A reagent for measuring immature leukocytes. |
摘要 |
<p>A reagent for measuring immature leukocytes which comprises: (1) a polyoxyethylene-based nonionic surfactant having the general formula (I) in a sufficient amount capable of fixing cytoplasms and cell membranes of immature leukocytes: R1-R2-(CH2CH2O)n-H (I) where R1 is an alkyl, alkenyl or alkynyl group having 10 to 25 carbon atoms; R2 is -O-, -(C6H4)-O- or -COO-; and n is an integer of 10 to 40, (2) a solubilizing agent in a sufficient amount capable of damaging cell membranes of blood cells other than immature leukocytes and shrinking them, (3) an amino acid in a sufficient amount capable of stabilizing cytoplasm and cell membrane of immature leukocytes, and (4) an aqueous medium, which adjusts pH value in the range of 5.0 to 9.0, osmolarity in the range of 150 to 600 mOsm/kg and electric conductivity in the range of 6.0 to 9.0 mS/cm, respectively.</p> |
申请公布号 |
EP0617281(A2) |
申请公布日期 |
1994.09.28 |
申请号 |
EP19940400580 |
申请日期 |
1994.03.17 |
申请人 |
TOA MEDICAL ELECTRONICS CO., LTD. |
发明人 |
TSUJINO, YUKIO;MORIKAWA, TAKASHI;HAMAGUCHI, YUKIO |
分类号 |
G01N33/48;G01N33/49;G01N33/50;(IPC1-7):G01N33/50;G01N33/569 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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