| 发明名称 |
CLONING GENES FROM STEPTOMYCES AVERMITILIS FOR AVERMECTIN BIOSYNTHESIS |
| 摘要 |
There are disclosed plasmids containing DNA isolated from Streptomyces avermitilis, the microorganism which is used to prepare avermectin compounds, identified as pAT1, pVE650 pVE855, pVE859, pVE1446, pVE923, and pVE924 which contain the genetic information for the biosynthesis of the avermectins. Methods for the isolation of such plasmid and for the manipulation of the plasmids to alter the formation of the avermectin compound are also disclosed. |
| 申请公布号 |
NZ233116(A) |
申请公布日期 |
1994.09.27 |
| 申请号 |
NZ19900233116 |
申请日期 |
1990.03.28 |
| 申请人 |
MERCK & CO INC |
发明人 |
GEWAIN, KEITH M;MACNEIL, DOUGLAS J;PARESS, PHILIP S;RUBY, CAROLYN L;STREICHER, STANLEY L;MACNEIL, TANYA |
| 分类号 |
C07D493/22;C07H17/08;C12N1/21;C12N9/10;C12N9/88;C12N15/09;C12N15/10;C12N15/52;C12N15/76;C12P17/18;C12P19/62;C12R1/19;C12R1/465;C12R1/47 |
主分类号 |
C07D493/22 |
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