| 发明名称 |
Aza-5,5-fused hetrocyclic acids as leukotriene antagonists |
| 摘要 |
Compounds having the formula I: <IMAGE> I are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.
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| 申请公布号 |
US5350760(A) |
申请公布日期 |
1994.09.27 |
| 申请号 |
US19930101882 |
申请日期 |
1993.08.04 |
| 申请人 |
MERCK FROSST CANADA, INC. |
发明人 |
LABELLE, MARK;XIANG, YIBIN;DUFRESNE, CLAUDE;BELLEY, MICHEL |
| 分类号 |
A61K31/42;A61K31/425;A61K45/06;A61P11/08;A61P29/00;C07D498/04;C07D513/04;(IPC1-7):C07D513/04 |
主分类号 |
A61K31/42 |
| 代理机构 |
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