PROTEINACEOUS PARTICLES CONTAINING RETROVIRAL ELEMENT

摘要

A DNA construct comprising (a) a single promoter; (b) a gag-derived sequence from a complex retrovirus; (c) a rev-like element; (d) an RRE-like element; and (e) donor and acceptor elements; wherein (i) elements (a) to (e) are arranged in such a fashion that in the construct that the promoter is capable of driving expression of both the gag-derived sequence and, by virtue of the donor and acceptor elements, the rev-like element; (ii) the construct does not contain a functional env gene.