| 摘要 |
The invention relates to the peptide drugs chrysospermines of the formula I <IMAGE> in which x and y denote, independently of one another, Aib or Iva, which are synthesised by the fungus Apiocrea chrysosperma during fermentation and accumulate in the culture broth, to a preparation process, to the use of the chrysospermines as pharmacological agents, in particular as agent against bacteria, fungi and/or nematodes and for the treatment of rejection reactions to organ transplants and of tumours, and to the microorganism Apiocrea chrysosperma DSM 7444. |
