发明名称 |
Vpr function and activity |
摘要 |
Pharmaceutical compositions comprising the HIV protein vpr or nucleic acid molecule encoding vpr are disclosed. Also disclosed are methods of treating patients suffering from diseases characterized by hyperproliferating undifferentiated cells such as cancer by administering such compositions. Methods of identifying compounds which have anti-HIV activity are disclosed, in particular, methods of identifying compounds which modulate the activity of vpr and of identifying compounds which inhibit vpr binding to the HIV protein gag. |
申请公布号 |
AU6252494(A) |
申请公布日期 |
1994.09.14 |
申请号 |
AU19940062524 |
申请日期 |
1994.02.22 |
申请人 |
DAVID B. WEINER |
发明人 |
DAVID B. WEINER;DAVID NATHAN LEVY;YOSEF REFAELI |
分类号 |
A61K38/00;A61K47/48;C07K14/16;G01N33/569 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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