| 摘要 |
Disclosed are novel iodophenoxy alkylene ethers of the formula: <IMG> ¢wherein Z is H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, alkoxycarbonyl or cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R is C1-C25 alkyl, cycloalkyl or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy-carbonyl or lower-alkoxy-carbonyloxy, (CR1R2)p-(CR3=CR4)mQ, (CR1R2)p-C?C-Q or <IMG> ; R1, R2, R3 and R4 are independently H, lower-alkyl, optionally substituted with halo; x and x' are 1-4; n and n' are 1-4; m is 1-15; p is 1-20; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, aryl or aryl-lower-alkyl! useful as contrast agents in diagnostic radiology of the gastrointestinal tract.
|
