发明名称 COMPOSITIONS OF IODOBENZOIC ACID DERIVATIVES IN FILM-FORMING MATERIALS FOR VISUALIZATION OF THE GASTROINTESTINAL TRACT
摘要 Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula wherein Z= H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, cyano, where the Alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R= C1-C25 alkyl, cycloalkyl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR1R2)p-(CR3=CR4)mQ,or(CR1R2)p-C?C-Q; R1, R2, R3 and R4 are independently lower-alkyl, optionally substituted with halo; x is 1-3 y is 1-4; n is 1-5; m is 1-15; p is 1-10; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl.
申请公布号 CA2116831(A1) 申请公布日期 1994.09.12
申请号 CA19942116831 申请日期 1994.03.02
申请人 STERLING WINTHROP INC. 发明人 ILLIG, CARL R.;DOUTY, BRENT D.
分类号 A61K47/30;A61K49/04;C08K5/07;(IPC1-7):A61K49/04 主分类号 A61K47/30
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