发明名称 Product from the coupling of histamine and an amino acid, process of preparation and therapeutic and cosmetological applications
摘要 The invention relates to a pseudodipeptide product obtained by coupling histamine or methyl-substituted histamine to an amino acid having the formula: <IMAGE> in which X represents a hydrogen atom or an acetyl group, R1, R'1, R2, R'2...Rn and R'n each represent a hydrogen atom or hydrocarbon radical which can be substituted by one or a number of functional groups, and n is an integer greater than or equal to 2, the covalent bond with histamine or methyl-substituted histamine being a peptide bond between the carboxyl radical of the amino acid and the amine radical of the histamine. The pseudodipeptide products of the invention can be used in therapeutic and cosmetological applications using their anti-ageing and anti-degeneration properties of tissues and mucous membranes, and in particular for the treatment of cataracts.
申请公布号 FR2701947(A1) 申请公布日期 1994.09.02
申请号 FR19930002295 申请日期 1993.02.22
申请人 EXSYMOL SA;BABIZHAYEV MARC 发明人 SEGUIN MARIE CHRISTINE;BABIZHAYEV MARC
分类号 A61K8/65;A61Q19/00;A61Q19/08;C07D233/54 主分类号 A61K8/65
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