发明名称 METHOD FOR OBTAINING AN INCREASED PRODUCTION OF A PRODUCING CELLINE BY USING A FUSION PROTOCOL
摘要 The invention relates to a method for obtaining a higher product expression in a producing mammalian celline characterized by treating the original celline with itself according to a fusion protocol known in the art. The production of protein products is performed in mammalian tissue culture, and the product could be therapeutic proteins or other molecules intended for human use. In particular this invention relates to the use of cell fusion methods to obtain a stable high producing celline.
申请公布号 CA2156181(A1) 申请公布日期 1994.09.01
申请号 CA19942156181 申请日期 1994.02.15
申请人 PHARMACIA AB 发明人 SPIRA, JACK;ADAMSSON, LARS
分类号 C12N15/02;C07K14/755;C12N5/10;C12N5/12;C12N5/16;(IPC1-7):C12N15/02;C12N13/00;C12N15/11 主分类号 C12N15/02
代理机构 代理人
主权项
地址