COMPOSITION AND BAG FOR PRESERVATION OF BLOOD PLATELETS

摘要

Provided is a storage composition for preventing cold-induced platelet activation, comprising, plasma containing a plurality of platelets; a non-naturally occurring first agent for inhibiting actin filament severing; and a non-naturally occurring second agent for inhibiting actin polymerization, wherein the first and second agents are present in the composition in sufficient amounts so as to prevent cold-induced platelet activation. Also provided is a composition for preventing cold-induced platelet activation, the composition comprising: a first agent for inhibiting actin filament severing; and a second agent for inhibiting actin polymerization, wherein said composition does not contain platelets. Further provided is a platelet bag containing: a first agent for inhibiting actin filament severing; and a second agent for inhibiting actin polymerization.