| 摘要 |
<p>A process for producing an intermediate for a 13,14-didehydroprostaglandin E, represented by general formula (I), (wherein R<6> represents -COOR<9>, cyano, hydroxy, -OCOR<10> or -CONR<11>R<12>; A represents vinylene, ethynylene, phenylene -C = C = C-; X represents oxygen or sulfur; m is 0 to 7; n, q and s are each 0 or 1; and p and r are each 0 to 5) by the free-radical reaction of a compound represented by general formula (II), with a compound represented by the following general formula: Y(CR<3>R<4>)mAn(CH2)pXq(CHR<5>)rR<6>, (wherein Y represents halogen or (a)) in the presence of a free-radical generator.</p> |
