NOVEL BENZOXAZINE DERIVATIVE, MEDICINE CONTAINING THE SAME, AND INTERMEDIATE THEREFOR

摘要

A benzoxazine derivative useful as a potassium channel activator and represented by general formula (I), a pharmaceutically acceptable salt thereof, a stereo-chemical isomer thereof, a medicinal composition containing the same, another benzoxazine derivative useful as an intermediate for the production thereof and represented by general formula (II), and a salt thereof. In formula (I), R<1> represents hydrogen, lower alkyl, lower alkanoyl, carbamoyl, mono- or di(lower alkyl)carbamoyl or nitro; R<2> represents lower alkyl; R<3> represents nitro; m represents an integer of 1 to 4; and n represents 0 or 1. In formula (II), R<1>, R<2>, R<3> and m are each as defined above.