AROMATIC STEROID 5-–-REDUCTASE INHIBITORS

摘要

AROMATIC STEROID 5-.alpha.-REDUCTASE INHIBITORS Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5-.alpha.-reductase including using these compounds to reduce prostate size. Also invented are intermediates used in preparing these compounds.