发明名称 |
Aminoketone derivatives of 1,2-oxazole and use thereof |
摘要 |
Aminoketone derivative compounds containing a heterocyclic ring bonded to an aminoketone moiety and useful as effective ingredients of centrally acting muscle relaxants and pollakiurea curing agents. (+)3-phenyl-5-[2-(1-pyrrolidinylmethyl)butyryl]isoxazole, which has a more remarkable central muscle relaxant action as compared with its racemic modification, can be effectively separated from the racemic modification using optically active 10-camphorsulfonic acid as the agent for the optical resolution.
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申请公布号 |
US5338857(A) |
申请公布日期 |
1994.08.16 |
申请号 |
US19920839434 |
申请日期 |
1992.02.24 |
申请人 |
MITSUI TOATSU CHEMICALS INCORPORATED |
发明人 |
OHTO, NORIO;HORIKOMI, KAZUTOSHI;MATSUBARA, AKIRA;TANADA, HIDEKI;SAKAI, KAZUYA;KAJIYA, SEITARO;MIZUCHI, AKIRA;SHIMIZU, HIDESHI |
分类号 |
C07D261/08;C07D261/10;C07D261/20;C07D275/02;C07D275/04;C07D413/04;C07D413/06;C07D417/06;(IPC1-7):C07D413/06;A61K31/42 |
主分类号 |
C07D261/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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