Benzoisothiazolinone-1-dioxide derivatives as elastase inhibitors
摘要
The invention relates to pharmaceutical and cosmetic compositions comprising at least one benzisothiazolinone-1-dioxide derivative with the formula: an be certain generally hydrophobic C8-C20 aliphatic groups or the group: <IMAGE> (III) where R5 is aliphatic or else R2 is a saturated or unsaturated C2-C6 group ending in an aromatic nucleus. These compositions can be used to inhibit elastases such as human leucocytic elastase. They may be applied topically as a cosmetic. Many of the benzisothiazolinone-1-dioxide derivative specified as active ingredient in such compositions are novel compounds.
申请公布号
US5338747(A)
申请公布日期
1994.08.16
申请号
US19910666093
申请日期
1991.03.07
申请人
CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC.
发明人
ROBERT, LADISLAS;MOCZAR, ELEMER;HORNEBECK, WILLIAM G.;KERNEUR, CHRISTIANE M. P.